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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL64260
Molecular formula	C22H28N2O4
IUPAC name	N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-2-methoxy-5-methylbenzamide
Molecular weight	384.476
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.0
Synonyms	BDBM50137617 N-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-2-methoxy-5-methyl-benzamide SCHEMBL8285666
Inchi Key	CKJPETQDQGIHJS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H28N2O4/c1-15-5-6-19(26-2)18(11-15)22(25)23-8-10-24-9-7-16-12-20(27-3)21(28-4)13-17(16)14-24/h5-6,11-13H,7-10,14H2,1-4H3,(H,23,25)
PubChem CID	11338096
ChEMBL	CHEMBL64260
IUPHAR	N/A
BindingDB	50137617
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
44107	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
44109	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
44108	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
44110	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446

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