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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	VU 0238429
Molecular formula	C17H12F3NO4
IUPAC name	1-[(4-methoxyphenyl)methyl]-5-(trifluoromethoxy)indole-2,3-dione
Molecular weight	351.281
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	3.5
Synonyms	VU0238429-1 CS-0003122 MFCD16618396 1-(4-METHOXYBENZYL)-5-TRIFLUOROMETHOXYISATIN B7448 DTXSID40655290 RT-017613 1160247-92-6 CHEMBL466253 J-003368 VU0238429 ZINC40875741 AKOS024457724 CTK8E8884 ML129 1-[(4-Methoxyphenyl)methyl]-5-(trifluoromethoxy)-1H-indole-2,3-dione BDBM50258656 GTPL3257 cid_42633508 KB-81463 VU0238429, solubility: >=20 mg/mL in DMSO 1-(4-methoxybenzyl)-5-(trifluoromethoxy)indoline-2,3-dione API0008325 D03DKZ MolPort-023-276-878 1-[(4-methoxyphenyl)methyl]-5-(trifluoromethoxy)-2,3-dihydro-1H-indole-2,3-dione HY-12157 VU-0238429 [ Show all ]
Inchi Key	CKLGZXFOLMHCMC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H12F3NO4/c1-24-11-4-2-10(3-5-11)9-21-14-7-6-12(25-17(18,19)20)8-13(14)15(22)16(21)23/h2-8H,9H2,1H3
PubChem CID	42633508
ChEMBL	CHEMBL466253
IUPHAR	3257
BindingDB	50258656
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
44161	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
44162	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
44164	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466
44167	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466
44165	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590
44163	Muscarinic acetylcholine receptor M4	P08173	CHRM4	Homo sapiens (Human)	479
44166	Muscarinic acetylcholine receptor M4	P08485	Chrm4	Rattus norvegicus (Rat)	478
44159	Muscarinic acetylcholine receptor M5	P08912	CHRM5	Homo sapiens (Human)	532
44160	Muscarinic acetylcholine receptor M5	P08911	Chrm5	Rattus norvegicus (Rat)	531

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