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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	1,3-Dipropyl-8-phenylxanthine
Molecular formula	C17H20N4O2
IUPAC name	8-phenyl-1,3-dipropyl-7H-purine-2,6-dione
Molecular weight	312.373
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.0
Synonyms	DB-056886 PDSP1_000990 1H-Purine-2,6,dione, 3,7-dihydro-1,3-dipropyl-8-phenyl- 8-phenyl-1,3-dipropyl-9H-purine-2,6-dione BDBM82025 CAS_128784 LS-126996 SCHEMBL661108 8-Phenyl-1,3-dipropyl-1H-purine-2,6(3H,7H)-dione AC1L2UFC CHEMBL158507 NCGC00024614-02 Tocris-0486 8-Phenyl-1,3-dipropyl-3,9-dihydro-purine-2,6-dione AKOS027320574 FT-0642015 PDSP2_000974 1H-Purine-2,6-dione, 3,7-dihydro-8-phenyl-1,3-dipropyl- BRD-K41853443-001-01-1 CHEBI:107631 MolPort-023-275-889 SR-01000597618 8-phenyl-1,3-dipropyl-1H-purine-2,6(3H,9H)-dione AC1Q6LCH CLIGSMOZKDCDRZ-UHFFFAOYSA-N NSC_128784 ZINC3995438 8-phenyl-1,3-dipropyl-7H-purine-2,6-dione BDBM50227332 BRD-K41853443-001-02-9 HMS3266E16 SCHEMBL12648449 3,7-Dihydro-1,3-dipropyl-8-phenyl-1H-purine-2,6,dione 85872-53-3 NCGC00024614-01 SR-01000597618-1 8-phenyl-1,3-dipropyl-3,9-dihydro-1h-purine-2,6-dione AKOS024458381 [ Show all ]
Inchi Key	CLIGSMOZKDCDRZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H20N4O2/c1-3-10-20-15-13(16(22)21(11-4-2)17(20)23)18-14(19-15)12-8-6-5-7-9-12/h5-9H,3-4,10-11H2,1-2H3,(H,18,19)
PubChem CID	128784
ChEMBL	CHEMBL158507
IUPHAR	N/A
BindingDB	82025
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
44738	Adenosine receptor A1	P28190	ADORA1	Bos taurus (Bovine)	326
44739	Adenosine receptor A1	P25099	Adora1	Rattus norvegicus (Rat)	326
44740	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412
44742	Adenosine receptor A2a	P46616	ADORA2A	Cavia porcellus (Guinea pig)	409
44743	Adenosine receptor A2a	P30543	Adora2a	Rattus norvegicus (Rat)	410
44741	Adenosine receptor A2b	P29275	ADORA2B	Homo sapiens (Human)	332

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