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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL60699
Molecular formula	C29H38N4O3
IUPAC name	9-benzyl-3-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-3,9-diazaspiro[5.5]undecane-2,4-dione
Molecular weight	490.648
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	2.9
Synonyms	9-Benzyl-3-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-3,9-diaza-spiro[5.5]undecane-2,4-dione BDBM50143657
Inchi Key	CSAAHSGMWAZWDZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H38N4O3/c1-36-26-10-6-5-9-25(26)32-18-15-30(16-19-32)17-20-33-27(34)21-29(22-28(33)35)11-13-31(14-12-29)23-24-7-3-2-4-8-24/h2-10H,11-23H2,1H3
PubChem CID	11191047
ChEMBL	CHEMBL60699
IUPHAR	N/A
BindingDB	50143657
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
49289	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
49288	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
49286	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
49287	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561

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