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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	UNII-87UKL3XE5X
Molecular formula	C22H26N4O2
IUPAC name	(8aS)-2-[(4-naphthalen-1-ylpiperazin-1-yl)methyl]-6,7,8,8a-tetrahydro-3H-pyrrolo[1,2-a]pyrazine-1,4-dione
Molecular weight	378.476
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	2.6
Synonyms	(-)-CSP-2503 LS-192630 581813-10-7 (S)-2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione Pyrrolo(1,2-a)pyrazine-1,4-dione, hexahydro-2-((4-(1-naphthalenyl)-1-piperazinyl)methyl)-, (8aS)- 87UKL3XE5X CHEMBL370758 BDBM50164450 [ Show all ]
Inchi Key	CTZWGZSINBFHFD-FQEVSTJZSA-N
Inchi ID	InChI=1S/C22H26N4O2/c27-21-15-25(22(28)20-9-4-10-26(20)21)16-23-11-13-24(14-12-23)19-8-3-6-17-5-1-2-7-18(17)19/h1-3,5-8,20H,4,9-16H2/t20-/m0/s1
PubChem CID	11291892
ChEMBL	CHEMBL370758
IUPHAR	N/A
BindingDB	50164450
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
50570	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
50571	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
50574	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
50572	5-hydroxytryptamine receptor 4	Q62758	Htr4	Rattus norvegicus (Rat)	406
50569	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
50573	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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