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Ligand

NameCHEMBL222489
Molecular formulaC27H36N4O2
IUPAC name2-[4-[6-oxo-6-(1,2,3,4-tetrahydronaphthalen-1-ylamino)hexyl]piperazin-1-yl]benzamide
Molecular weight448.611
Hydrogen bond acceptor4
Hydrogen bond donor2
XlogP3.3
Synonyms2-{4-[5-(1,2,3,4-tetrahydronaphthalen-1-ylcarbamoyl)pentyl]piperazin-1-yl}benzamide
BDBM21376
Piperazinehexanamide derivative, 14
Inchi KeyCUNIRIUQESLLLU-UHFFFAOYSA-N
Inchi IDInChI=1S/C27H36N4O2/c28-27(33)23-12-5-6-14-25(23)31-19-17-30(18-20-31)16-7-1-2-15-26(32)29-24-13-8-10-21-9-3-4-11-22(21)24/h3-6,9,11-12,14,24H,1-2,7-8,10,13,15-20H2,(H2,28,33)(H,29,32)
PubChem CID11341394
ChEMBLCHEMBL222489
IUPHARN/A
BindingDB21376
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 5
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
509475-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
509485-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
509515-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
509505-hydroxytryptamine receptor 7P32305Htr7Rattus norvegicus (Rat)448
50949D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443

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