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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MK 1903
Molecular formula	C8H8N2O2
IUPAC name	(2R,4R)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid
Molecular weight	164.164
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	0.6
Synonyms	SCHEMBL11972373 (4aR,5aR)-4,4a,5,5a-Tetrahydro-1H-cyclopropa(4,5)cyclopenta(1,2-C)pyrazole-3-carboxylic acid KB-274625 ZINC35923551 1H-Cyclopropa(4,5)cyclopenta(1,2-C)pyrazole-3-carboxylic acid, 4,4a,5,5a-tetrahydro-, (4aR,5aR)- MolPort-035-765-775 (1aR,5aR)-1a,2,5,5a-tetrahydro-1H-2,3-diazacyclopropa[a]pentalene-4-carboxylic Acid AKOS024458259 CHEMBL2057618 SCHEMBL4481866 (4aR,5aR)-4,4a,5,5a-Tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2]pyrazole-3-carboxylic acid NCGC00379170-01 (1aR,5aR)-1a,3,5,5a-Tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalene-4-carboxylic acid BDBM50388230 CUTZNERBKDMLAP-QWWZWVQMSA-N UNII-62N05GRI0P 1268882-43-4 mk-1903 (1aR, 5aR)-1a,3,5,5a-Tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalene-4-carboxylic acid 62N05GRI0P [ Show all ]
Inchi Key	CUTZNERBKDMLAP-QWWZWVQMSA-N
Inchi ID	InChI=1S/C8H8N2O2/c11-8(12)7-5-2-3-1-4(3)6(5)9-10-7/h3-4H,1-2H2,(H,9,10)(H,11,12)/t3-,4-/m1/s1
PubChem CID	49763030
ChEMBL	CHEMBL2057618
IUPHAR	N/A
BindingDB	50388230
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
51120	Hydroxycarboxylic acid receptor 2	Q8TDS4	HCAR2	Homo sapiens (Human)	363

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