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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL397121
Molecular formula	C18H13F2N3O
IUPAC name	4-(3,5-difluorophenyl)-N-(6-methylpyridin-2-yl)pyridine-2-carboxamide
Molecular weight	325.319
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.5
Synonyms	4-(3,5-Difluorophenyl)-N-(6-methylpyrindin-2-yl)picolinamide 4-(3,5-difluorophenyl)-N-(6-methylpyridin-2-yl)picolinamide BDBM50207078 SCHEMBL8163804
Inchi Key	CVBWBHLJBLFSFF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H13F2N3O/c1-11-3-2-4-17(22-11)23-18(24)16-9-12(5-6-21-16)13-7-14(19)10-15(20)8-13/h2-10H,1H3,(H,22,23,24)
PubChem CID	16730836
ChEMBL	CHEMBL397121
IUPHAR	N/A
BindingDB	50207078
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
51353	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
51350	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
51351	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
51352	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877

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