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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL87943
Molecular formula	C24H26FNO2
IUPAC name	2-[2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl]-3,4-dihydro-2H-naphthalen-1-one
Molecular weight	379.475
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	4.4
Synonyms	BDBM50409509 LS-95098 QF-0303B SCHEMBL13904319
Inchi Key	CWYWUEUVHLRQJP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H26FNO2/c25-21-9-7-18(8-10-21)23(27)20-12-15-26(16-13-20)14-11-19-6-5-17-3-1-2-4-22(17)24(19)28/h1-4,7-10,19-20H,5-6,11-16H2
PubChem CID	9886130
ChEMBL	CHEMBL87943
IUPHAR	N/A
BindingDB	50409509
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
52601	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
52602	5-hydroxytryptamine receptor 2B	P30994	Htr2b	Rattus norvegicus (Rat)	479
52599	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
52603	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
52600	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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