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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	L-249313
Molecular formula	C18H16N4O2
IUPAC name	methyl 9-methyl-2-phenyl-5H-[1,2,4]triazolo[5,1-a][2,7]naphthyridine-6-carboxylate
Molecular weight	320.352
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	1.6
Synonyms	AC1N966E CHEMBL52735 methyl 9-methyl-2-phenyl-5H-[1,2,4]triazolo[5,1-a][2,7]naphthyridine-6-carboxylate BDBM50059376 D0Y8SB 9-Methyl-2-phenyl-5,9-dihydro-[1,2,4]triazolo[5,1-a][2,7]naphthyridine-6-carboxylic acid methyl ester SCHEMBL13932309 [ Show all ]
Inchi Key	DBROFPXBIMMIMF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H16N4O2/c1-21-9-8-13-14(10-21)17-19-16(12-6-4-3-5-7-12)20-22(17)11-15(13)18(23)24-2/h3-10H,11H2,1-2H3
PubChem CID	4355631
ChEMBL	CHEMBL52735
IUPHAR	N/A
BindingDB	50059376
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
55945	Adenosine receptor A1	P30542	ADORA1	Homo sapiens (Human)	326
55946	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412
55943	Adenosine receptor A2b	P29275	ADORA2B	Homo sapiens (Human)	332
55947	Adenosine receptor A2b	P29276	Adora2b	Rattus norvegicus (Rat)	332
55944	Adenosine receptor A3	P0DMS8	ADORA3	Homo sapiens (Human)	318

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