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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1084738
Molecular formula	C27H23F3N4O
IUPAC name	[(3R)-3-methyl-4-[4-[4-(trifluoromethyl)phenyl]phthalazin-1-yl]piperazin-1-yl]-phenylmethanone
Molecular weight	476.503
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	5.5
Synonyms	(R)-(3-methyl-4-(4-(4-(trifluoromethyl)phenyl)phthalazin-1-yl)piperazin-1-yl)(phenyl)methanone BDBM50320369 SCHEMBL1090951
Inchi Key	DEEQMQGTBCCINJ-GOSISDBHSA-N
Inchi ID	InChI=1S/C27H23F3N4O/c1-18-17-33(26(35)20-7-3-2-4-8-20)15-16-34(18)25-23-10-6-5-9-22(23)24(31-32-25)19-11-13-21(14-12-19)27(28,29)30/h2-14,18H,15-17H2,1H3/t18-/m1/s1
PubChem CID	25255940
ChEMBL	CHEMBL1084738
IUPHAR	N/A
BindingDB	50320369
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
57700	Smoothened homolog	Q99835	SMO	Homo sapiens (Human)	787
57701	Smoothened homolog	P56726	Smo	Mus musculus (Mouse)	793

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