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Ligand

NameCHEMBL433296
Molecular formulaC34H43N11O5
IUPAC name(2S)-2-[[(2R)-2-[[(2S)-2-acetamido-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-N-[(2R)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-5-(diaminomethylideneamino)pentanamide
Molecular weight685.79
Hydrogen bond acceptor7
Hydrogen bond donor9
XlogP-0.3
SynonymsAc-His-DPhe-Arg-DTrp-NH2
Ac-His-DPhe-DArg-DTrp-NH2
BDBM50058963
Inchi KeyDFCJPPDAOZROBS-AUAHOFGGSA-N
Inchi IDInChI=1S/C34H43N11O5/c1-20(46)42-29(16-23-18-38-19-41-23)33(50)45-28(14-21-8-3-2-4-9-21)32(49)43-26(12-7-13-39-34(36)37)31(48)44-27(30(35)47)15-22-17-40-25-11-6-5-10-24(22)25/h2-6,8-11,17-19,26-29,40H,7,12-16H2,1H3,(H2,35,47)(H,38,41)(H,42,46)(H,43,49)(H,44,48)(H,45,50)(H4,36,37,39)/t26-,27+,28+,29-/m0/s1
PubChem CID9896284
ChEMBLCHEMBL433296
IUPHARN/A
BindingDB50058963
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has more than 5 hydrogen bond donor.
This ligand is heavier than 500 daltons.

Known GPCRs

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Total entries: 8
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
58379Melanocortin receptor 3P41968MC3RHomo sapiens (Human)323
58381Melanocortin receptor 3P33033Mc3rMus musculus (Mouse)323
58385Melanocortin receptor 4P56450Mc4rMus musculus (Mouse)332
459758Melanocortin receptor 4P32245MC4RHomo sapiens (Human)332
58383Melanocortin receptor 5P41149Mc5rMus musculus (Mouse)325
58386Melanocortin receptor 5P33032MC5RHomo sapiens (Human)325
58382Melanocyte-stimulating hormone receptorQ01727Mc1rMus musculus (Mouse)315
459757Melanocyte-stimulating hormone receptorQ01726MC1RHomo sapiens (Human)317

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