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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL264190
Molecular formula	C34H43N11O5
IUPAC name	(2S)-2-[[(2R)-2-[[(2S)-2-acetamido-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-N-[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-5-(diaminomethylideneamino)pentanamide
Molecular weight	685.79
Hydrogen bond acceptor	7
Hydrogen bond donor	9
XlogP	-0.3
Synonyms	Ac-His(6)-DPhe(7)-Arg(8)-Trp(9)-NH(2) CTK0E8618 (S)-2-{(R)-2-[(S)-2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide Ac-His-DPhe-Arg-Trp-NH(2) 2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid [1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide Ac-His-D-Phe-Arg-Trp-NH(2) JRH-887-9 149969-04-0 Ac-His-DPhe-Arg-Trp-NH2 (S)-2-{(R)-2-[(S)-2-Acetylamino-3-(1H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide Ac-His-D-Phe-Arg-Trp-NH2 L-Tryptophanamide, N-acetyl-L-histidyl-D-phenylalanyl-L-arginyl- 1N-[1-carbamoyl-2-(1H-3-indolyl)-(1S)-ethyl]-5-amino(imino)methylamino-2-[1-[2-(1H-5-imidazolyl)-1-methylcarboxamido-(1S)-ethylcarboxamido]-2-phenyl-(1R)-ethylcarboxamido]-(2S)-pentanamide BDBM50034922 [ Show all ]
Inchi Key	DFCJPPDAOZROBS-FKWFRFQNSA-N
Inchi ID	InChI=1S/C34H43N11O5/c1-20(46)42-29(16-23-18-38-19-41-23)33(50)45-28(14-21-8-3-2-4-9-21)32(49)43-26(12-7-13-39-34(36)37)31(48)44-27(30(35)47)15-22-17-40-25-11-6-5-10-24(22)25/h2-6,8-11,17-19,26-29,40H,7,12-16H2,1H3,(H2,35,47)(H,38,41)(H,42,46)(H,43,49)(H,44,48)(H,45,50)(H4,36,37,39)/t26-,27-,28+,29-/m0/s1
PubChem CID	11093672
ChEMBL	CHEMBL264190
IUPHAR	N/A
BindingDB	50034922
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
58406	Melanocortin receptor 3	P33033	Mc3r	Mus musculus (Mouse)	323
58407	Melanocortin receptor 3	P41968	MC3R	Homo sapiens (Human)	323
58404	Melanocortin receptor 4	P56450	Mc4r	Mus musculus (Mouse)	332
58405	Melanocortin receptor 4	P32245	MC4R	Homo sapiens (Human)	332
58402	Melanocortin receptor 5	P41149	Mc5r	Mus musculus (Mouse)	325
58408	Melanocortin receptor 5	P33032	MC5R	Homo sapiens (Human)	325
58403	Melanocyte-stimulating hormone receptor	Q01727	Mc1r	Mus musculus (Mouse)	315
58409	Melanocyte-stimulating hormone receptor	Q01726	MC1R	Homo sapiens (Human)	317

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