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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1671877
Molecular formula	C14H14F2N2O3
IUPAC name	5-(3-cyclopropylpropyl)-2-(difluoromethyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione
Molecular weight	296.274
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	2.3
Synonyms	5-(3-cyclopropylpropyl)-2-(difluoromethyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione BDBM50337038 SCHEMBL12560406
Inchi Key	DFLJUOUAVYDDBB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H14F2N2O3/c15-11(16)12-17-13(20)10-8(3-1-2-7-4-5-7)6-9(19)21-14(10)18-12/h6-7,11H,1-5H2,(H,17,18,20)
PubChem CID	51346919
ChEMBL	CHEMBL1671877
IUPHAR	N/A
BindingDB	50337038
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
58659	Hydroxycarboxylic acid receptor 2	Q9EP66	Hcar2	Mus musculus (Mouse)	360
58661	Hydroxycarboxylic acid receptor 2	Q80Z39	Hcar2	Rattus norvegicus (Rat)	360
58662	Hydroxycarboxylic acid receptor 2	Q8TDS4	HCAR2	Homo sapiens (Human)	363
58660	Hydroxycarboxylic acid receptor 3	P49019	HCAR3	Homo sapiens (Human)	387

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