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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000147834
Molecular formula	C20H18N6O3S
IUPAC name	4,6-diamino-14-(3,4-dimethoxyphenyl)-8-imino-12-oxo-9-thia-3,11-diazatricyclo[8.4.0.02,7]tetradeca-1(10),2(7),3,5-tetraene-5-carbonitrile
Molecular weight	422.463
Hydrogen bond acceptor	9
Hydrogen bond donor	4
XlogP	1.0
Synonyms	AKOS005568493 MLS000556517 REGID_for_CID_6077070 6,8-Diamino-4-(3,4-dimethoxy-phenyl)-9-imino-2-oxo-1,3,4,9-tetrahydro-2H-10-thia-1,5-diaza-phenant hrene-7-carbonitrile HMS2383D24 AKOS030519743 MolPort-002-585-162 2,4-diamino-10-(3,4-dimethoxyphenyl)-5-imino-8-oxo-7,8,9,10-tetrahydro-5H-thiopyrano[2,3-b:4,5-b']dipyridine-3-carbonitrile CHEMBL1361038 647830-21-5 MCULE-8996116510 BDBM97076 MolPort-005-979-928 2,4-diamino-10-(3,4-dimethoxyphenyl)-8-hydroxy-5-imino-9,10-dihydro-5H-thiopyrano[2,3-b:4,5-b']dipyridine-3-carbonitrile cid_6077070 STK636556 [ Show all ]
Inchi Key	DGBHQVQZJNSRNC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H18N6O3S/c1-28-11-4-3-8(5-12(11)29-2)9-6-13(27)25-20-14(9)17-15(19(24)30-20)16(22)10(7-21)18(23)26-17/h3-5,9,24H,6H2,1-2H3,(H,25,27)(H4,22,23,26)
PubChem CID	4352110
ChEMBL	CHEMBL1361038
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
559107	Galanin receptor type 3	O60755	GALR3	Homo sapiens (Human)	368
559108	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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