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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AC1O2QT2
Molecular formula	C20H16N4O
IUPAC name	(4Z)-4-[(1,3-diphenylpyrazol-4-yl)methylidene]-3-methyl-1H-pyrazol-5-one
Molecular weight	328.375
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	3.3
Synonyms	CHEMBL1447306 SCHEMBL17481616 AKOS002802326 HMS2662E19 (4Z)-4-[(1,3-diphenylpyrazol-4-yl)methylene]-3-methyl-1H-pyrazol-5-one PubChem SID: 24781057 [ Show all ]
Inchi Key	DGSFFYVACCJJGR-PDGQHHTCSA-N
Inchi ID	InChI=1S/C20H16N4O/c1-14-18(20(25)22-21-14)12-16-13-24(17-10-6-3-7-11-17)23-19(16)15-8-4-2-5-9-15/h2-13H,1H3,(H,22,25)/b18-12-
PubChem CID	6258408
ChEMBL	CHEMBL1447306
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
59552	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
59553	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
470270	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593
59555	Sphingosine 1-phosphate receptor 1	P21453	S1PR1	Homo sapiens (Human)	382
59554	Sphingosine 1-phosphate receptor 4	O95977	S1PR4	Homo sapiens (Human)	384

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