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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL149491
Molecular formula	C17H22N2O
IUPAC name	3-[(1S,13R)-4-hydroxy-1,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-10-yl]propanenitrile
Molecular weight	270.376
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	1.5
Synonyms	BDBM50095694 CHEMBL2368133 3-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2,6-methano-benzo[d]azocin-3-yl)-propionitrile
Inchi Key	DHJAHFWTVDJKOO-VUOHQMJNSA-N
Inchi ID	InChI=1S/C17H22N2O/c1-12-16-10-13-4-5-14(20)11-15(13)17(12,2)6-9-19(16)8-3-7-18/h4-5,11-12,16,20H,3,6,8-10H2,1-2H3/t12-,16?,17-/m0/s1
PubChem CID	73351409
ChEMBL	CHEMBL2368133
IUPHAR	N/A
BindingDB	50095694
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
60044	Delta-type opioid receptor	P32300	Oprd1	Mus musculus (Mouse)	372
60046	Kappa-type opioid receptor	P33534	Oprk1	Mus musculus (Mouse)	380
60045	Mu-type opioid receptor	P42866	Oprm1	Mus musculus (Mouse)	398

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