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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL76525
Molecular formula	C26H32N4O5S2
IUPAC name	2-butyl-5-methylsulfanyl-3-[[4-[2-(propylcarbamoylsulfamoyl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid
Molecular weight	544.685
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	5.1
Synonyms	2-Butyl-3-(N''-propylureidylsulfonyl-biphenyl-4-ylmethyl)-5-methylsulfanyl-3H-imidazole-4-carboxylic acid(HR720) BDBM50031537 1-[[2'-(3-Propylureidosulfonyl)biphenyl-4-yl]methyl]-2-butyl-4-(methylthio)-1H-imidazole-5-carboxylic acid SCHEMBL7701057 5-carboxyl imidazolyl biphenyl sulfonylurea derivative 2-butyl-1-[[2''-[[[(propylamino)carbonyl]amino]sulfonyl]-(1,1''-biphenyl)-4yl]methyl]-4-(methylthio)-1H-imidazole-5-carboxylic acid [ Show all ]
Inchi Key	DKCCTYVLJMSFOG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H32N4O5S2/c1-4-6-11-22-28-24(36-3)23(25(31)32)30(22)17-18-12-14-19(15-13-18)20-9-7-8-10-21(20)37(34,35)29-26(33)27-16-5-2/h7-10,12-15H,4-6,11,16-17H2,1-3H3,(H,31,32)(H2,27,29,33)
PubChem CID	9809280
ChEMBL	CHEMBL76525
IUPHAR	N/A
BindingDB	50031537
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
62082	Type-2 angiotensin II receptor	P50052	AGTR2	Homo sapiens (Human)	363

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