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Ligand

NameCHEMBL168571
Molecular formulaC21H24N4O
IUPAC name(4R)-2-phenyl-4-[(4-phenylpiperazin-1-yl)methyl]-4,5-dihydro-1H-pyrimidin-6-one
Molecular weight348.45
Hydrogen bond acceptor4
Hydrogen bond donor1
XlogP2.3
SynonymsBDBM50124194
(6R)-2-Phenyl-6alpha-(4-phenylpiperazinomethyl)-3,4,5,6-tetrahydropyrimidine-4-one
(R)-2-Phenyl-6-(4-phenyl-piperazin-1-ylmethyl)-5,6-dihydro-3H-pyrimidin-4-one
Inchi KeyDKXYPAWNMBQJBN-GOSISDBHSA-N
Inchi IDInChI=1S/C21H24N4O/c26-20-15-18(22-21(23-20)17-7-3-1-4-8-17)16-24-11-13-25(14-12-24)19-9-5-2-6-10-19/h1-10,18H,11-16H2,(H,22,23,26)/t18-/m1/s1
PubChem CID44381279
ChEMBLCHEMBL168571
IUPHARN/A
BindingDB50124194
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 4
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
62702D(1A) dopamine receptorQ95136DRD1Bos taurus (Bovine)446
62700D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
62703D(3) dopamine receptorP35462DRD3Homo sapiens (Human)400
62701D(4) dopamine receptorP21917DRD4Homo sapiens (Human)467

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