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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL25000
Molecular formula	C28H29N7O
IUPAC name	2-butyl-6-(dimethylamino)-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]quinazolin-4-one
Molecular weight	479.588
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.7
Synonyms	BDBM50281955 2-Butyl-6-dimethylamino-3-[2''-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-quinazolin-4-one
Inchi Key	DLRKOOXBINYYRU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H29N7O/c1-4-5-10-26-29-25-16-15-21(34(2)3)17-24(25)28(36)35(26)18-19-11-13-20(14-12-19)22-8-6-7-9-23(22)27-30-32-33-31-27/h6-9,11-17H,4-5,10,18H2,1-3H3,(H,30,31,32,33)
PubChem CID	44274671
ChEMBL	CHEMBL25000
IUPHAR	N/A
BindingDB	50281955
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
63277	Type-1 angiotensin II receptor	P34976	AGTR1	Oryctolagus cuniculus (Rabbit)	359
63276	Type-2 angiotensin II receptor	P50052	AGTR2	Homo sapiens (Human)	363

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