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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000033110
Molecular formula	C12H11N5O2S
IUPAC name	1-ethyl-6-methyl-3-thiophen-2-ylpyrimido[5,4-e][1,2,4]triazine-5,7-dione
Molecular weight	289.313
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	1.4
Synonyms	MCULE-7994907095 ST50002655 1-ethyl-6-methyl-3-(2-thienyl)-6-hydropyrimidino[5,4-e]1,2,4-triazine-5,7-dion e AKOS001873422 CCG-144085 NCGC00034880-03 1-Ethyl-6-methyl-3-thiophen-2-yl-1H-pyrimido[5,4-e][1,2,4]triazine-5,7-dione cid_653297 SCHEMBL10195758 BAS 00444322 STK177227 1-ethyl-6-methyl-3-(2-thienyl)pyrimido[5,4-e][1,2,4]triazine-5,7-quinone Oprea1_582234 1-ethyl-6-methyl-3-thiophen-2-yl-pyrimido[5,4-e][1,2,4]triazine-5,7-dione HMS2184P06 SMR000008918 AC1LCO3U BDBM31044 NCGC00034880-02 US9073941, 610 1-ethyl-6-methyl-3-(thiophen-2-yl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione CHEMBL555689 Oprea1_633836 1-ethyl-6-methyl-3-thiophen-2-ylpyrimido[5,4-e][1,2,4]triazine-5,7-dione [ Show all ]
Inchi Key	DMDNERFCUCYCGM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H11N5O2S/c1-3-17-10-8(11(18)16(2)12(19)14-10)13-9(15-17)7-5-4-6-20-7/h4-6H,3H2,1-2H3
PubChem CID	653297
ChEMBL	CHEMBL555689
IUPHAR	N/A
BindingDB	31044
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
63576	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
63577	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
63572	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
63575	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
470733	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593
63573	Sphingosine 1-phosphate receptor 1	P21453	S1PR1	Homo sapiens (Human)	382
63574	Sphingosine 1-phosphate receptor 3	Q99500	S1PR3	Homo sapiens (Human)	378
63578	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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