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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AC1LCLHZ
Molecular formula	C25H23NO6
IUPAC name	2-(3,4-dimethoxyphenyl)-3-(furan-2-carbonyl)-4-hydroxy-1-(2-phenylethyl)-2H-pyrrol-5-one
Molecular weight	433.46
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.3
Synonyms	5-(3,4-dimethoxyphenyl)-4-(furan-2-carbonyl)-3-hydroxy-1-(2-phenylethyl)-2,5-dihydro-1H-pyrrol-2-one CHEMBL1539091 MolPort-000-192-935 BAS 05885106 5-(3,4-dimethoxyphenyl)-4-(furan-2-ylcarbonyl)-3-hydroxy-1-(2-phenylethyl)-1,5-dihydro-2H-pyrrol-2-one HMS2345C18 AKOS000527607 STK819782 2-(3,4-dimethoxyphenyl)-3-(furan-2-carbonyl)-4-hydroxy-1-phenethyl-2H-pyrrol-5-one 607336-29-8 MCULE-1080916954 AKOS016060528 Z57790227 [ Show all ]
Inchi Key	DMFFTBJDDXUOMK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H23NO6/c1-30-18-11-10-17(15-20(18)31-2)22-21(23(27)19-9-6-14-32-19)24(28)25(29)26(22)13-12-16-7-4-3-5-8-16/h3-11,14-15,22,28H,12-13H2,1-2H3
PubChem CID	652107
ChEMBL	CHEMBL1539091
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
470744	fMet-Leu-Phe receptor	P21462	FPR1	Homo sapiens (Human)	350

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