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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL218486
Molecular formula	C25H32BrClN6O4S
IUPAC name	2-(2-bromophenyl)-1-[4-chloro-3-[3-[(2R,6S)-2,6-dimethylmorpholin-4-yl]pentan-3-ylsulfamoyl]-2-hydroxyphenyl]-3-cyanoguanidine
Molecular weight	627.983
Hydrogen bond acceptor	8
Hydrogen bond donor	4
XlogP	6.1
Synonyms	BDBM50193978 3-(2-bromophenyl)-1-[4-chloro-3-({3-[(2R,6S)-2,6-dimethylmorpholin-4-yl]pentan-3-yl}sulfamoyl)-2-hydroxyphenyl]-2-cyanoguanidine
Inchi Key	DNQSYCVLRVJIIH-CALCHBBNSA-N
Inchi ID	InChI=1S/C25H32BrClN6O4S/c1-5-25(6-2,33-13-16(3)37-17(4)14-33)32-38(35,36)23-19(27)11-12-21(22(23)34)31-24(29-15-28)30-20-10-8-7-9-18(20)26/h7-12,16-17,32,34H,5-6,13-14H2,1-4H3,(H2,29,30,31)/t16-,17+
PubChem CID	44419473
ChEMBL	CHEMBL218486
IUPHAR	N/A
BindingDB	50193978
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
64591	C-X-C chemokine receptor type 1	P25024	CXCR1	Homo sapiens (Human)	350
64592	C-X-C chemokine receptor type 2	P25025	CXCR2	Homo sapiens (Human)	360

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