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Ligand

NameMK 0893
Molecular formulaC32H27Cl2N3O4
IUPAC name3-[[4-[(1S)-1-[3-(3,5-dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)pyrazol-1-yl]ethyl]benzoyl]amino]propanoic acid
Molecular weight588.485
Hydrogen bond acceptor5
Hydrogen bond donor2
XlogP6.8
Synonyms(S)-3-(4-(1-(3-(3,5-Dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)-1H-pyrazol-1-yl)ethyl)benzamido)propanoic acid
3-[[4-[(1S)-1-[3-(3,5-dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)pyrazol-1-yl]ethyl]benzoyl]amino]propanoic acid
3-[[4-[(1~{s})-1-[3-[3,5-Bis(Chloranyl)phenyl]-5-(6-Methoxynaphthalen-2-Yl)pyrazol-1-Yl]ethyl]phenyl]carbonylamino]propanoic Acid
3736AC
5MV
[ Show all ]
Inchi KeyDNTVJEMGHBIUMW-IBGZPJMESA-N
Inchi IDInChI=1S/C32H27Cl2N3O4/c1-19(20-3-5-21(6-4-20)32(40)35-12-11-31(38)39)37-30(18-29(36-37)25-14-26(33)17-27(34)15-25)24-8-7-23-16-28(41-2)10-9-22(23)13-24/h3-10,13-19H,11-12H2,1-2H3,(H,35,40)(H,38,39)/t19-/m0/s1
PubChem CID11570626
ChEMBLCHEMBL1933349
IUPHAR9135
BindingDB50360601
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand is heavier than 500 daltons.
This ligand has a partition coefficient log P greater than 5.

Known GPCRs

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Total entries: 8
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
64644Gastric inhibitory polypeptide receptorP48546GIPRHomo sapiens (Human)466
64645Glucagon receptorP47871GCGRHomo sapiens (Human)477
64646Glucagon receptorQ61606GcgrMus musculus (Mouse)485
64649Glucagon receptorP30082GcgrRattus norvegicus (Rat)485
64648Glucagon-like peptide 1 receptorP43220GLP1RHomo sapiens (Human)463
553573Pituitary adenylate cyclase-activating polypeptide type I receptorP41586ADCYAP1R1Homo sapiens (Human)468
64647Vasoactive intestinal polypeptide receptor 1P32241VIPR1Homo sapiens (Human)457
64650Vasoactive intestinal polypeptide receptor 2P41587VIPR2Homo sapiens (Human)438

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