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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL455406
Molecular formula	C30H32N4O4
IUPAC name	6-[benzyl(ethyl)amino]-2-(2,6-dimethoxypyridin-3-yl)-N-(2-phenoxyethyl)pyridine-3-carboxamide
Molecular weight	512.61
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	5.3
Synonyms	6-[benzyl(ethyl)amino]-2-(2,6-dimethoxypyridin-3-yl)-N-(2-phenoxyethyl)pyridine-3-carboxamide BDBM28016 trisubstituted pyridine analogue, 18b
Inchi Key	DPISCHMOAFKKEG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C30H32N4O4/c1-4-34(21-22-11-7-5-8-12-22)26-17-15-24(29(35)31-19-20-38-23-13-9-6-10-14-23)28(32-26)25-16-18-27(36-2)33-30(25)37-3/h5-18H,4,19-21H2,1-3H3,(H,31,35)
PubChem CID	25218733
ChEMBL	CHEMBL455406
IUPHAR	N/A
BindingDB	28016
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
65676	Extracellular calcium-sensing receptor	P41180	CASR	Homo sapiens (Human)	1078

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