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Ligand

NameSNAP-7915
Molecular formulaC25H28F3N3O3
IUPAC name(4S,5S)-4-(3,4-difluorophenyl)-N-[3-[4-(4-fluorophenyl)piperidin-1-yl]propyl]-5-methyl-2-oxo-1,3-oxazolidine-3-carboxamide
Molecular weight475.512
Hydrogen bond acceptor7
Hydrogen bond donor1
XlogP5.0
SynonymsCHEMBL96467
SNAP7915
D0D8GV
SCHEMBL7658901
DTYAFBJXWWLRMA-QMHKHESXSA-N
[ Show all ]
Inchi KeyDTYAFBJXWWLRMA-QMHKHESXSA-N
Inchi IDInChI=1S/C25H28F3N3O3/c1-16-23(19-5-8-21(27)22(28)15-19)31(25(33)34-16)24(32)29-11-2-12-30-13-9-18(10-14-30)17-3-6-20(26)7-4-17/h3-8,15-16,18,23H,2,9-14H2,1H3,(H,29,32)/t16-,23+/m0/s1
PubChem CID9830741
ChEMBLCHEMBL96467
IUPHARN/A
BindingDB50090647
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 15
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
687815-hydroxytryptamine receptor 1AQ64264Htr1aMus musculus (Mouse)421
687895-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
687935-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
687915-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
68784Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
68787Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
68786Alpha-1B adrenergic receptorP35368ADRA1BHomo sapiens (Human)520
68795Alpha-1B adrenergic receptorP15823Adra1bRattus norvegicus (Rat)515
68785Alpha-1D adrenergic receptorP23944Adra1dRattus norvegicus (Rat)561
68788Alpha-1D adrenergic receptorP25100ADRA1DHomo sapiens (Human)572
68790Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
68782Alpha-2B adrenergic receptorP18089ADRA2BHomo sapiens (Human)450
68792Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462
68783Histamine H1 receptorP35367HRH1Homo sapiens (Human)487
68794Histamine H2 receptorP25021HRH2Homo sapiens (Human)359

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