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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3641729
Molecular formula	C15H16F2N4O2
IUPAC name	5-(difluoromethoxy)-N-[4-[(2R)-morpholin-2-yl]phenyl]pyrimidin-2-amine
Molecular weight	322.316
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	2.0
Synonyms	SCHEMBL12609698 US8802673, 179 BDBM129537 DUCFIFULTZWOSS-ZDUSSCGKSA-N (R)-5-(difluoromethoxy)-N-(4-(morpholin-2-yl)phenyl)pyrimidin-2-amine
Inchi Key	DUCFIFULTZWOSS-ZDUSSCGKSA-N
Inchi ID	InChI=1S/C15H16F2N4O2/c16-14(17)23-12-7-19-15(20-8-12)21-11-3-1-10(2-4-11)13-9-18-5-6-22-13/h1-4,7-8,13-14,18H,5-6,9H2,(H,19,20,21)/t13-/m0/s1
PubChem CID	68325483
ChEMBL	CHEMBL3641729
IUPHAR	N/A
BindingDB	129537
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
68871	Trace amine-associated receptor 1	Q923Y8	Taar1	Mus musculus (Mouse)	332
68872	Trace amine-associated receptor 7b	Q923X8	Taar7b	Rattus norvegicus (Rat)	358

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