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Ligand

NameCHEMBL328187
Molecular formulaC27H30FN7O
IUPAC name1-[2-[4-[1-(4-fluorophenyl)-5-(1-methyltriazol-4-yl)indol-3-yl]piperidin-1-yl]ethyl]imidazolidin-2-one
Molecular weight487.583
Hydrogen bond acceptor5
Hydrogen bond donor1
XlogP2.9
Synonyms1-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-[1,2,3]triazol-4-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one
BDBM50122807
L019142
SCHEMBL6967889
Inchi KeyDUTDDZFCPPOWFH-UHFFFAOYSA-N
Inchi IDInChI=1S/C27H30FN7O/c1-32-18-25(30-31-32)20-2-7-26-23(16-20)24(17-35(26)22-5-3-21(28)4-6-22)19-8-11-33(12-9-19)14-15-34-13-10-29-27(34)36/h2-7,16-19H,8-15H2,1H3,(H,29,36)
PubChem CID9848303
ChEMBLCHEMBL328187
IUPHARN/A
BindingDB50122807
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 11
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
694005-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
693975-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
693965-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
693985-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
694025-hydroxytryptamine receptor 2CP08909Htr2cRattus norvegicus (Rat)460
69395Alpha-1A adrenergic receptorP18130ADRA1ABos taurus (Bovine)466
69394Alpha-1B adrenergic receptorP18841ADRA1BMesocricetus auratus (Golden hamster)515
69392Alpha-1D adrenergic receptorP23944Adra1dRattus norvegicus (Rat)561
69393D(2) dopamine receptorP61169Drd2Rattus norvegicus (Rat)444
69399D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
69401Histamine H1 receptorP35367HRH1Homo sapiens (Human)487

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