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Ligand

NameCHEMBL93923
Molecular formulaC28H31FN6O
IUPAC name1-[2-[4-[1-(4-fluorophenyl)-5-(1-methylpyrazol-3-yl)indol-3-yl]piperidin-1-yl]ethyl]imidazolidin-2-one
Molecular weight486.595
Hydrogen bond acceptor4
Hydrogen bond donor1
XlogP3.4
SynonymsSCHEMBL6962059
BDBM50122799
1-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-pyrazol-3-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one
Inchi KeyDVICNJMXCZEIQX-UHFFFAOYSA-N
Inchi IDInChI=1S/C28H31FN6O/c1-32-12-10-26(31-32)21-2-7-27-24(18-21)25(19-35(27)23-5-3-22(29)4-6-23)20-8-13-33(14-9-20)16-17-34-15-11-30-28(34)36/h2-7,10,12,18-20H,8-9,11,13-17H2,1H3,(H,30,36)
PubChem CID11049209
ChEMBLCHEMBL93923
IUPHARN/A
BindingDB50122799
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 10
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
699485-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
699545-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
699555-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
699515-hydroxytryptamine receptor 2CP08909Htr2cRattus norvegicus (Rat)460
69950Alpha-1A adrenergic receptorP18130ADRA1ABos taurus (Bovine)466
69949Alpha-1B adrenergic receptorP18841ADRA1BMesocricetus auratus (Golden hamster)515
69946Alpha-1D adrenergic receptorP23944Adra1dRattus norvegicus (Rat)561
69953D(2) dopamine receptorP61169Drd2Rattus norvegicus (Rat)444
69947D(3) dopamine receptorP35462DRD3Homo sapiens (Human)400
69952D(4) dopamine receptorP21917DRD4Homo sapiens (Human)467

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