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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1788223
Molecular formula	C23H27N5OS
IUPAC name	(3S)-3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-5-methylsulfanyl-2,3-dihydroimidazo[1,2-c]quinazoline
Molecular weight	421.563
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	3.2
Synonyms	(3S)-3-[[4-(2-Methoxyphenyl)piperazin-1-yl]methyl]-5-(methylthio)-2,3-dihydroimidazo[1,2-c]quinazoline BDBM50369382
Inchi Key	DVYBIZHLZSDANU-QGZVFWFLSA-N
Inchi ID	InChI=1S/C23H27N5OS/c1-29-21-10-6-5-9-20(21)27-13-11-26(12-14-27)16-17-15-24-22-18-7-3-4-8-19(18)25-23(30-2)28(17)22/h3-10,17H,11-16H2,1-2H3/t17-/m1/s1
PubChem CID	9931977
ChEMBL	CHEMBL1788223
IUPHAR	N/A
BindingDB	50369382
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
70362	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
70363	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
70361	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
70368	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
70364	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
70365	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
70366	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
70367	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488

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