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Ligand

NameCHEMBL1788223
Molecular formulaC23H27N5OS
IUPAC name(3S)-3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-5-methylsulfanyl-2,3-dihydroimidazo[1,2-c]quinazoline
Molecular weight421.563
Hydrogen bond acceptor6
Hydrogen bond donor0
XlogP3.2
SynonymsBDBM50369382
(3S)-3-[[4-(2-Methoxyphenyl)piperazin-1-yl]methyl]-5-(methylthio)-2,3-dihydroimidazo[1,2-c]quinazoline
Inchi KeyDVYBIZHLZSDANU-QGZVFWFLSA-N
Inchi IDInChI=1S/C23H27N5OS/c1-29-21-10-6-5-9-20(21)27-13-11-26(12-14-27)16-17-15-24-22-18-7-3-4-8-19(18)25-23(30-2)28(17)22/h3-10,17H,11-16H2,1-2H3/t17-/m1/s1
PubChem CID9931977
ChEMBLCHEMBL1788223
IUPHARN/A
BindingDB50369382
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 8
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
703625-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
70363Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
70361Alpha-1B adrenergic receptorP15823Adra1bRattus norvegicus (Rat)515
70368Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
70364Alpha-2B adrenergic receptorP18089ADRA2BHomo sapiens (Human)450
70365D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
70366D(3) dopamine receptorP35462DRD3Homo sapiens (Human)400
70367Histamine H1 receptorP31389HRH1Cavia porcellus (Guinea pig)488

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