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Ligand

NameCHEMBL2036319
Molecular formulaC27H28N2O5S2
IUPAC name2-[2-[(2R)-2-[(E,3S)-3-hydroxy-4-[3-(4-methoxyphenyl)phenyl]but-1-enyl]-5-oxopyrrolidin-1-yl]ethylsulfanyl]-1,3-thiazole-4-carboxylic acid
Molecular weight524.65
Hydrogen bond acceptor8
Hydrogen bond donor2
XlogP4.5
SynonymsSCHEMBL10210674
BDBM50385129
Inchi KeyDWLBFFMLIQEQIV-ORMBLBCUSA-N
Inchi IDInChI=1S/C27H28N2O5S2/c1-34-23-10-5-19(6-11-23)20-4-2-3-18(15-20)16-22(30)9-7-21-8-12-25(31)29(21)13-14-35-27-28-24(17-36-27)26(32)33/h2-7,9-11,15,17,21-22,30H,8,12-14,16H2,1H3,(H,32,33)/b9-7+/t21-,22+/m0/s1
PubChem CID57894063
ChEMBLCHEMBL2036319
IUPHARN/A
BindingDB50385129
DrugBankN/A

Structure

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2D structure
Lipinski's druglikenessThis ligand is heavier than 500 daltons.

Known GPCRs

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Total entries: 6
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
70661Prostaglandin E2 receptor EP1 subtypeP35375Ptger1Mus musculus (Mouse)405
70662Prostaglandin E2 receptor EP2 subtypeQ62928Ptger2Rattus norvegicus (Rat)357
70665Prostaglandin E2 receptor EP2 subtypeQ62053Ptger2Mus musculus (Mouse)362
70666Prostaglandin E2 receptor EP3 subtypeP30557Ptger3Mus musculus (Mouse)365
70663Prostaglandin E2 receptor EP4 subtypeP32240Ptger4Mus musculus (Mouse)513
70664Prostaglandin E2 receptor EP4 subtypeP43114Ptger4Rattus norvegicus (Rat)488

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