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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL355135
Molecular formula	C18H16BrN3O
IUPAC name	1-(2-bromo-4-propan-2-ylphenyl)-4-methyl-6-oxo-7H-pyrrolo[2,3-b]pyridine-3-carbonitrile
Molecular weight	370.25
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	3.5
Synonyms	1-(2-Bromo-4-isopropylphenyl)-4-methyl-6-hydroxy-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile 1-(2-Bromo-4-isopropyl-phenyl)-6-hydroxy-4-methyl-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile BDBM50074416
Inchi Key	DZHYYJXOBIBELN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H16BrN3O/c1-10(2)12-4-5-15(14(19)7-12)22-9-13(8-20)17-11(3)6-16(23)21-18(17)22/h4-7,9-10H,1-3H3,(H,21,23)
PubChem CID	10809156
ChEMBL	CHEMBL355135
IUPHAR	N/A
BindingDB	50074416
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
72672	Corticotropin-releasing factor receptor 1	P35353	Crhr1	Rattus norvegicus (Rat)	415

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