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Ligand

NameCHEMBL2079655
Molecular formulaC19H28N6O3
IUPAC name(2R)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-N-tert-butylpiperazine-2-carboxamide
Molecular weight388.472
Hydrogen bond acceptor8
Hydrogen bond donor3
XlogP1.3
SynonymsSCHEMBL7818716
BDBM50455469
Inchi KeyFACJCZHMOYUSSW-CYBMUJFWSA-N
Inchi IDInChI=1S/C19H28N6O3/c1-19(2,3)24-17(26)13-10-25(7-6-21-13)18-22-12-9-15(28-5)14(27-4)8-11(12)16(20)23-18/h8-9,13,21H,6-7,10H2,1-5H3,(H,24,26)(H2,20,22,23)/t13-/m1/s1
PubChem CID10643994
ChEMBLCHEMBL2079655
IUPHARN/A
BindingDB50455469
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 3
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
73276Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
73275Alpha-1B adrenergic receptorP15823Adra1bRattus norvegicus (Rat)515
73274Alpha-1D adrenergic receptorP23944Adra1dRattus norvegicus (Rat)561

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