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Ligand

Namepramipexole
Molecular formulaC10H17N3S
IUPAC name(6S)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
Molecular weight211.327
Hydrogen bond acceptor4
Hydrogen bond donor2
XlogP1.9
Synonyms104632-26-0
(-)-Pramipexole
Pramipexol
Sifrol
Mirapexin
[ Show all ]
Inchi KeyFASDKYOPVNHBLU-ZETCQYMHSA-N
Inchi IDInChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)/t7-/m0/s1
PubChem CID119570
ChEMBLCHEMBL301265
IUPHAR953
BindingDB50116766
DrugBankDB00413

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 19
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
737515-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
737585-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
737535-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
737545-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
737485-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
737575-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
73750Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
73759Alpha-2B adrenergic receptorP18089ADRA2BHomo sapiens (Human)450
73747Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462
73752D(1A) dopamine receptorQ95136DRD1Bos taurus (Bovine)446
73756D(1A) dopamine receptorP18901Drd1Rattus norvegicus (Rat)446
73760D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446
73749D(1B) dopamine receptorP21918DRD5Homo sapiens (Human)477
73742D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
73744D(2) dopamine receptorP20288DRD2Bos taurus (Bovine)444
73746D(2) dopamine receptorP61169Drd2Rattus norvegicus (Rat)444
73745D(3) dopamine receptorP35462DRD3Homo sapiens (Human)400
73755D(3) dopamine receptorP19020Drd3Rattus norvegicus (Rat)446
73743D(4) dopamine receptorP21917DRD4Homo sapiens (Human)467

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