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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000675932
Molecular formula	C16H12ClN3O3S
IUPAC name	5-chloro-2-methylsulfonyl-N-naphthalen-2-ylpyrimidine-4-carboxamide
Molecular weight	361.8
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.8
Synonyms	5-chloro-2-methylsulfonyl-N-(2-naphthalenyl)-4-pyrimidinecarboxamide CHEMBL1480031 STK913227 5-CHLORO-2-(METHYLSULFONYL)-N-(2-NAPHTHYL)-4-PYRIMIDINECARBOXAMIDE AC1Q4GKY MCULE-5416058210 5-chloro-2-mesyl-N-(2-naphthyl)pyrimidine-4-carboxamide BRD-K89789994-001-04-7 Oprea1_780451 325724-72-9 5-chloro-2-methylsulfonyl-N-naphthalen-2-ylpyrimidine-4-carboxamide cid_991251 Z56771875 5-chloro-2-(methylsulfonyl)-N-(naphthalen-2-yl)pyrimidine-4-carboxamide AKOS001017159 5-chloro-2-methanesulfonyl-N-(naphthalen-2-yl)pyrimidine-4-carboxamide SMR000297158 5-chloranyl-2-methylsulfonyl-N-naphthalen-2-yl-pyrimidine-4-carboxamide AC1LKHDD HMS2620G05 ZINC643945 5-chloro-2-(methylsulfonyl)-N-2-naphthyl-4-pyrimidinecarboxamide BDBM70951 MolPort-000-399-019 [ Show all ]
Inchi Key	FCEVPKDAWILUQM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H12ClN3O3S/c1-24(22,23)16-18-9-13(17)14(20-16)15(21)19-12-7-6-10-4-2-3-5-11(10)8-12/h2-9H,1H3,(H,19,21)
PubChem CID	991251
ChEMBL	CHEMBL1480031
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
74855	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
74856	Lutropin-choriogonadotropic hormone receptor	P22888	LHCGR	Homo sapiens (Human)	699
74854	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
472134	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593
74852	Sphingosine 1-phosphate receptor 1	P21453	S1PR1	Homo sapiens (Human)	382
74853	Sphingosine 1-phosphate receptor 4	O95977	S1PR4	Homo sapiens (Human)	384
74851	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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