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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	(S)-zacopride
Molecular formula	C15H20ClN3O2
IUPAC name	4-amino-N-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-5-chloro-2-methoxybenzamide
Molecular weight	309.794
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	1.7
Synonyms	4-Amino-N-(S)-1-aza-bicyclo[2.2.2]oct-3-yl-5-chloro-2-methoxy-benzamide D0I4BZ UNII-9GN3OT4156 component FEROPKNOYKURCJ-CYBMUJFWSA-N PDSP1_001634 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-((S)-methoxy)-benzamide SCHEMBL5373467 4-amino-N-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-5-chloro-2-methoxybenzamide GTPL2289 ZACOPRIDE,R AC1O7H1O PDSP2_001618 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide CHEMBL28992 Tocris-1795 4-amino-N-[(8S)-1-azabicyclo[2.2.2]octan-8-yl]-5-chloro-2-methoxybenzamide NCGC00025295-01 ZINC3961 BDBM50056419 SCHEMBL16233195 [ Show all ]
Inchi Key	FEROPKNOYKURCJ-CYBMUJFWSA-N
Inchi ID	InChI=1S/C15H20ClN3O2/c1-21-14-7-12(17)11(16)6-10(14)15(20)18-13-8-19-4-2-9(13)3-5-19/h6-7,9,13H,2-5,8,17H2,1H3,(H,18,20)/t13-/m1/s1
PubChem CID	6604914
ChEMBL	CHEMBL28992
IUPHAR	N/A
BindingDB	50056419
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
76562	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388
76563	5-hydroxytryptamine receptor 4	Q62758	Htr4	Rattus norvegicus (Rat)	406
76564	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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