Home Research Services Publications People Teaching Job Opening Facilities News Forum Lab Only
Online Services

I-TASSER QUARK LOMETS COACH COFACTOR MetaGO MUSTER SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH BSpred SVMSEQ ANGLOR BSP-SLIM SAXSTER ThreaDom ThreaDomEx EvoDesign GPCR-I-TASSER BindProf BindProfX ResQ IonCom STRUM DAMpred

TM-score TM-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR NeBcon WDL-RF ATPbind DockRMSD

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

You can:

Ligand

NameCHEMBL1259188
Molecular formulaC27H31FN8O
IUPAC name1-[2-[4-[1-(4-fluorophenyl)-5-[(2-methyltetrazol-5-yl)methyl]indol-3-yl]piperidin-1-yl]ethyl]imidazolidin-2-one
Molecular weight502.598
Hydrogen bond acceptor6
Hydrogen bond donor1
XlogP3.6
Synonyms1-(2-(4-(1-(4-fluorophenyl)-5-((2-methyl-2H-tetrazol-5-yl)methyl)-1H-indol-3-yl)piperidin-1-yl)ethyl)imidazolidin-2-one
BDBM50328476
SCHEMBL6954429
Inchi KeyFGHKCRNDQSRICR-UHFFFAOYSA-N
Inchi IDInChI=1S/C27H31FN8O/c1-33-31-26(30-32-33)17-19-2-7-25-23(16-19)24(18-36(25)22-5-3-21(28)4-6-22)20-8-11-34(12-9-20)14-15-35-13-10-29-27(35)37/h2-7,16,18,20H,8-15,17H2,1H3,(H,29,37)
PubChem CID9913988
ChEMBLCHEMBL1259188
IUPHARN/A
BindingDB50328476
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand is heavier than 500 daltons.

Known GPCRs

You can:

Total entries: 4
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
77776Alpha-1A adrenergic receptorP18130ADRA1ABos taurus (Bovine)466
77778Alpha-1B adrenergic receptorP18841ADRA1BMesocricetus auratus (Golden hamster)515
77775Alpha-1D adrenergic receptorP23944Adra1dRattus norvegicus (Rat)561
77777D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443

yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218