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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1813117
Molecular formula	C28H25ClN2O5
IUPAC name	2-[5-chloro-2-methyl-1-[4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]indol-3-yl]acetic acid
Molecular weight	504.967
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	5.9
Synonyms	BDBM50350368 SCHEMBL5643680
Inchi Key	FGWQXWPDBISCQU-NRFANRHFSA-N
Inchi ID	InChI=1S/C28H25ClN2O5/c1-17-22(14-27(32)33)23-13-19(29)9-12-24(23)31(17)28(34)18-7-10-20(11-8-18)35-16-21-15-30(2)25-5-3-4-6-26(25)36-21/h3-13,21H,14-16H2,1-2H3,(H,32,33)/t21-/m0/s1
PubChem CID	10185612
ChEMBL	CHEMBL1813117
IUPHAR	N/A
BindingDB	50350368
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
78137	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
78138	Prostaglandin D2 receptor	P70263	Ptgdr	Mus musculus (Mouse)	357
78136	Prostaglandin E2 receptor EP1 subtype	P35375	Ptger1	Mus musculus (Mouse)	405
78139	Prostaglandin E2 receptor EP2 subtype	Q62053	Ptger2	Mus musculus (Mouse)	362
78135	Prostaglandin E2 receptor EP3 subtype	P30557	Ptger3	Mus musculus (Mouse)	365
78134	Prostaglandin E2 receptor EP4 subtype	P32240	Ptger4	Mus musculus (Mouse)	513
78140	Prostaglandin F2-alpha receptor	P43117	Ptgfr	Mus musculus (Mouse)	366

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