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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	1-Methylhistamine
Molecular formula	C6H11N3
IUPAC name	2-(1-methylimidazol-4-yl)ethanamine
Molecular weight	125.175
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	-0.6
Synonyms	2-(1-Methyl-1H-imidazol-4-yl)ethylamine BRN 0110757 D0A4XL Histamine, 1-methyl- LS-78032 N-tele-Methylhistamine NCGC00162240-01 1,4-methylhistamine SB15504 4-(1-aminoethyl)-1-methyl-1H-imidazole AC1Q4VOV CHEBI:29009 FHQDWPCFSJMNCT-UHFFFAOYSA-N Imidazole, 4-(2-aminoethyl)-1-methyl- (8CI) N( 1)-Methylhistamine N.tau.-Methylhistamine NSC66736 1-Methyl-4-(2-aminoethyl)imidazole Tele-methylhistamine 1H-Imidazole-4-ethanamine, 1-methyl- 2-(1-methyl-1H-imidazol-4-yl)ethan-1-amine 5-25-09-00527 (Beilstein Handbook Reference) AS-50436 CS-0054396 GTPL1241 Lopac-M-4910 N(tele)-methylhistamine NCGC00015677-02 PDSP1_000511 1-Methyl-4-histamine [2-(1-methyl-1H-imidazol-4-yl)ethyl]amine 2-(1-Methyl-1H-imidazol-4-yl)ethylamine # AC1L1GBQ C05127 D0T6SC HY-W062542 MCULE-7688329107 N-Telle-methylhistamine NSC 66736 1-Methyl-1H-imidazole-4-ethanamine SCHEMBL196356 1H-Imidazole-4-ethanamine, 1-methyl- (9CI) 4-(2-aminoethyl)-1-methyl-Imidazole AF9B9F65-564B-4C50-B4AF-F195114242DE FT-0608087 KCB81T4EOF N(1)-methylhistamine N1-Methylhistamine NT-methylhistamine 1-methyl-4-(b-aminoethyl)imidazole UNII-KCB81T4EOF 2-(1-methyl-1H-imidazol-4-yl)ethanamine 501-75-7 BDBM50198912 CTK4J2221 GTPL1242 Lopac0_000757 N-tele methylhistamine NCGC00015677-03 PDSP2_000509 2-(1-methylimidazol-4-yl)ethanamine AC1Q3Z1K CCG-204842 DTXSID30198207 Imidazole, 4-(2-aminoethyl)-1-methyl- MolPort-006-803-985 N-[3H]methylhistamine NSC-66736 1-Methyl-4-(.beta.-aminoethyl)imidazole SCHEMBL3826532 1H-IMIDAZOLE, 4-(1-AMINOETHYL)-1-METHYL- 1H-Imidazole-4-ethanamine,1-methyl- 4-(2-Aminoethyl)-1-methylimidazole AKOS006350836 CHEMBL507 FT-0701318 L000842 N(sup 1)-Methylhistamine NCGC00015677-01 Ntau-Methylhistamine 1-Methyl-4-(beta-aminoethyl)imidazole ZINC403051 [ Show all ]
Inchi Key	FHQDWPCFSJMNCT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C6H11N3/c1-9-4-6(2-3-7)8-5-9/h4-5H,2-3,7H2,1H3
PubChem CID	3614
ChEMBL	CHEMBL507
IUPHAR	1241, 1242
BindingDB	50198912
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
78571	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488
78572	Histamine H2 receptor	P47747	HRH2	Cavia porcellus (Guinea pig)	359
78570	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
553660	Histamine H3 receptor	Q9QYN8	Hrh3	Rattus norvegicus (Rat)	445
78574	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390
553658	Histamine H4 receptor	Q91ZY2	Hrh4	Mus musculus (Mouse)	391
553659	Histamine H4 receptor	Q91ZY1	Hrh4	Rattus norvegicus (Rat)	391
78573	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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