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Ligand

NamePizotifen
Molecular formulaC19H21NS
IUPAC name1-methyl-4-(6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-2-ylidene)piperidine
Molecular weight295.444
Hydrogen bond acceptor2
Hydrogen bond donor0
XlogP3.8
SynonymsPIZOTYLINE
15574-96-6
Sandomigran
Litec
Sandomygran
[ Show all ]
Inchi KeyFIADGNVRKBPQEU-UHFFFAOYSA-N
Inchi IDInChI=1S/C19H21NS/c1-20-11-8-15(9-12-20)19-16-5-3-2-4-14(16)6-7-18-17(19)10-13-21-18/h2-5,10,13H,6-9,11-12H2,1H3
PubChem CID27400
ChEMBLCHEMBL294951
IUPHAR93
BindingDB82088
DrugBankDB06153

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 21
Page:  / 2 

GLASS IDNameUniProtGeneSpeciesLength
788595-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
788615-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
5488215-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
788635-hydroxytryptamine receptor 1DP79400HTR1DSus scrofa (Pig)291
5488135-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
788625-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
788605-hydroxytryptamine receptor 2BP30994Htr2bRattus norvegicus (Rat)479
788665-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
788675-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
788645-hydroxytryptamine receptor 7P34969HTR7Homo sapiens (Human)479
548812Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
548814Alpha-1B adrenergic receptorP35368ADRA1BHomo sapiens (Human)520
548819Alpha-1D adrenergic receptorP25100ADRA1DHomo sapiens (Human)572
548822Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
548818Alpha-2B adrenergic receptorP18089ADRA2BHomo sapiens (Human)450
548820Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462
78868D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
548817Histamine H1 receptorP35367HRH1Homo sapiens (Human)487
78865Muscarinic acetylcholine receptor M1P11229CHRM1Homo sapiens (Human)460
548816Muscarinic acetylcholine receptor M2P08172CHRM2Homo sapiens (Human)466

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