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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL378972
Molecular formula	C32H33F2N3O
IUPAC name	3-[4-[4-(3-cyanophenyl)phenyl]-1-cyclopentylpiperidin-4-yl]-N-(3,5-difluorophenyl)propanamide
Molecular weight	513.633
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	6.5
Synonyms	3-[4-(3''-cyano-biphenyl-4-yl)-1-cyclopentyl-piperidin-4-yl]-N-(3,5-difluoro-phenyl)-propionamide BDBM50186820
Inchi Key	FJLGKUVQHVCSRB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C32H33F2N3O/c33-27-19-28(34)21-29(20-27)36-31(38)12-13-32(14-16-37(17-15-32)30-6-1-2-7-30)26-10-8-24(9-11-26)25-5-3-4-23(18-25)22-35/h3-5,8-11,18-21,30H,1-2,6-7,12-17H2,(H,36,38)
PubChem CID	20608977
ChEMBL	CHEMBL378972
IUPHAR	N/A
BindingDB	50186820
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
79850	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
79849	Melanin-concentrating hormone receptor 2	Q969V1	MCHR2	Homo sapiens (Human)	340

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