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Ligand

NameSpiramide
Molecular formulaC22H26FN3O2
IUPAC name8-[3-(4-fluorophenoxy)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Molecular weight383.467
Hydrogen bond acceptor5
Hydrogen bond donor1
XlogP3.4
SynonymsAMI-193
Spiramidum
Fluroxyspiramine
Espiramida
510-74-7
[ Show all ]
Inchi KeyFJUKDAZEABGEIH-UHFFFAOYSA-N
Inchi IDInChI=1S/C22H26FN3O2/c23-18-7-9-20(10-8-18)28-16-4-13-25-14-11-22(12-15-25)21(27)24-17-26(22)19-5-2-1-3-6-19/h1-3,5-10H,4,11-17H2,(H,24,27)
PubChem CID68186
ChEMBLCHEMBL79834
IUPHAR175
BindingDB86525
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 7
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
800795-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
800755-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
800745-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
800775-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
800805-hydroxytryptamine receptor 2CP08909Htr2cRattus norvegicus (Rat)460
80078D(1A) dopamine receptorQ61616Drd1Mus musculus (Mouse)446
80076D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443

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