Zhang Lab

University of Michigan

Home Research COVID-19 Services Publications People Teaching Job Opening News Forum Lab Only

Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1783985
Molecular formula	C15H25NO
IUPAC name	2-azaspiro[5.5]undecan-2-yl(cyclobutyl)methanone
Molecular weight	235.371
Hydrogen bond acceptor	1
Hydrogen bond donor	0
XlogP	3.4
Synonyms	AKOS033138150 BDBM50346073 cyclobutyl(2-azaspiro[5.5]undecan-2-yl)methanone MolPort-028-765-023
Inchi Key	FKNJDTXOOMHZMJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H25NO/c17-14(13-6-4-7-13)16-11-5-10-15(12-16)8-2-1-3-9-15/h13H,1-12H2
PubChem CID	54582001
ChEMBL	CHEMBL1783985
IUPHAR	N/A
BindingDB	50346073
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
80653	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
80652	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
80650	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
80654	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
80649	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
80651	Metabotropic glutamate receptor 7	Q14831	GRM7	Homo sapiens (Human)	915
80655	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

zhanglabzhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218