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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000060793
Molecular formula	C23H31N3O6S
IUPAC name	2-[4-[2-hydroxy-3-(4-morpholin-4-ylsulfonylphenoxy)propyl]piperazin-1-yl]phenol
Molecular weight	477.576
Hydrogen bond acceptor	9
Hydrogen bond donor	2
XlogP	1.3
Synonyms	2-[4-[2-hydroxy-3-(4-morpholin-4-ylsulfonylphenoxy)propyl]piperazin-1-yl]phenol MCULE-4697345090 AC1MHC2Q MolPort-004-247-305 CHEMBL1350084 716375-94-9 MLS000054455 AKOS034456039 2-(4-{2-hydroxy-3-[4-(morpholine-4-sulfonyl)phenoxy]propyl}piperazin-1-yl)phenol HMS2493G22 AB00425576-09 MLS000879856 Z56798524 [ Show all ]
Inchi Key	FNAQITQLNSNPNB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H31N3O6S/c27-19(17-24-9-11-25(12-10-24)22-3-1-2-4-23(22)28)18-32-20-5-7-21(8-6-20)33(29,30)26-13-15-31-16-14-26/h1-8,19,27-28H,9-18H2
PubChem CID	2999575
ChEMBL	CHEMBL1350084
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
82441	5-hydroxytryptamine receptor 2A	P35363	Htr2a	Mus musculus (Mouse)	471
473058	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
82440	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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