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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000119525
Molecular formula	C22H25F3N2O3
IUPAC name	N-[2-(cyclohexylamino)-1-(furan-2-yl)-2-oxoethyl]-2,2,2-trifluoro-N-(2-phenylethyl)acetamide
Molecular weight	422.448
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.7
Synonyms	AKOS000802007 MLS002538425 MCULE-2107148834 AKOS024316339 N-(Cyclohexylcarbamoyl-furan-2-yl-methyl)-2,2,2-trifluoro-N-phenethyl-acetamide CHEMBL1496220 AC1ML8D8 MLS000122112 ASN 05990728 N-[2-(cyclohexylamino)-1-(furan-2-yl)-2-oxoethyl]-2,2,2-trifluoro-N-phenethylacetamide HMS2382P22 [ Show all ]
Inchi Key	FRZVXUNJFRLXDY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H25F3N2O3/c23-22(24,25)21(29)27(14-13-16-8-3-1-4-9-16)19(18-12-7-15-30-18)20(28)26-17-10-5-2-6-11-17/h1,3-4,7-9,12,15,17,19H,2,5-6,10-11,13-14H2,(H,26,28)
PubChem CID	3215983
ChEMBL	CHEMBL1496220
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
85893	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
85895	Lutropin-choriogonadotropic hormone receptor	P22888	LHCGR	Homo sapiens (Human)	699
85894	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
85896	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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