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Ligand

Name2-methyl-N-[2-methyl-1-(phenylcarbonyl)-1,2,3,4-tetrahydroquinolin-4-yl]-N-phenylpropanamide
Molecular formulaC27H28N2O2
IUPAC nameN-(1-benzoyl-2-methyl-3,4-dihydro-2H-quinolin-4-yl)-2-methyl-N-phenylpropanamide
Molecular weight412.533
Hydrogen bond acceptor2
Hydrogen bond donor0
XlogP5.4
SynonymsAC1MWFTS
SCHEMBL5397963
BDBM86692
MolPort-002-939-186
STK063474
[ Show all ]
Inchi KeyFTCWKSGDHXCEMZ-UHFFFAOYSA-N
Inchi IDInChI=1S/C27H28N2O2/c1-19(2)26(30)29(22-14-8-5-9-15-22)25-18-20(3)28(24-17-11-10-16-23(24)25)27(31)21-12-6-4-7-13-21/h4-17,19-20,25H,18H2,1-3H3
PubChem CID3723424
ChEMBLN/A
IUPHARN/A
BindingDB86692
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has a partition coefficient log P greater than 5.

Known GPCRs

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Total entries: 13
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
5557905-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
86626Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
86625Alpha-2A adrenergic receptorP22909Adra2aRattus norvegicus (Rat)450
86631Cysteinyl leukotriene receptor 1Q9Y271CYSLTR1Homo sapiens (Human)337
86624D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446
555788D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
86630Histamine H1 receptorP35367HRH1Homo sapiens (Human)487
86628Histamine H2 receptorP25021HRH2Homo sapiens (Human)359
555789Leukotriene B4 receptor 2Q9NPC1LTB4R2Homo sapiens (Human)358
86629Muscarinic acetylcholine receptor M1P11229CHRM1Homo sapiens (Human)460
86632Platelet-activating factor receptorP25105PTAFRHomo sapiens (Human)342
86627Prostaglandin D2 receptorQ13258PTGDRHomo sapiens (Human)359
555787Thromboxane A2 receptorP21731TBXA2RHomo sapiens (Human)343

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