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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL415446
Molecular formula	C21H23N3O4S
IUPAC name	2-hydroxy-N,N-dimethyl-3-[[2-[[(1R)-1-(5-methylthiophen-2-yl)propyl]amino]-3,4-dioxocyclobuten-1-yl]amino]benzamide
Molecular weight	413.492
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	3.7
Synonyms	BDBM50200877 SCHEMBL12262763 (R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylthiophen-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide
Inchi Key	FVNZKJFLVPSOMX-CYBMUJFWSA-N
Inchi ID	InChI=1S/C21H23N3O4S/c1-5-13(15-10-9-11(2)29-15)22-16-17(20(27)19(16)26)23-14-8-6-7-12(18(14)25)21(28)24(3)4/h6-10,13,22-23,25H,5H2,1-4H3/t13-/m1/s1
PubChem CID	16098486
ChEMBL	CHEMBL415446
IUPHAR	N/A
BindingDB	50200877
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
88353	C-X-C chemokine receptor type 1	P25024	CXCR1	Homo sapiens (Human)	350
88354	C-X-C chemokine receptor type 2	P25025	CXCR2	Homo sapiens (Human)	360

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