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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Ethyl 2-amino-4-methyl-5-phenylthiophene-3-carboxylate
Molecular formula	C14H15NO2S
IUPAC name	ethyl 2-amino-4-methyl-5-phenylthiophene-3-carboxylate
Molecular weight	261.339
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.1
Synonyms	ethyl 2-amino-4-methyl-5-phenylthiophene 3-carboxylate MolPort-001-757-982 STK791088 BDBM50299471 FXPVOLWQNNGFHA-UHFFFAOYSA-N SCHEMBL4217459 ZINC37360 2-Amino-4-methyl-5-phenyl-thiophene-3-carboxylic acid ethyl ester AJ-08747 CHEMBL566136 DTXSID20350150 MCULE-9930283305 SR-01000396531-1 3-Thiophenecarboxylicacid, 2-amino-4-methyl-5-phenyl-, ethyl ester BAS 00899395 NE11645 Z56938146 AC1LDSFI CCG-103720 HMS2504J22 SMR000116331 2-Amino-4-methyl-5-phenylthiophene-3-carboxylic acid ethyl ester AKOS000674703 CTK4J0694 EN300-06910 MLS000525857 ST033546 4815-38-7 BB 0218696 FT-0766367 SBB000996 ZERO/001328 AC1Q334W KB-50859 SR-01000396531 3-Thiophenecarboxylic acid, 2-amino-4-methyl-5-phenyl-, ethyl ester ALBB-032293 DB-014788 [ Show all ]
Inchi Key	FXPVOLWQNNGFHA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H15NO2S/c1-3-17-14(16)11-9(2)12(18-13(11)15)10-7-5-4-6-8-10/h4-8H,3,15H2,1-2H3
PubChem CID	674768
ChEMBL	CHEMBL566136
IUPHAR	N/A
BindingDB	50299471
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
89829	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
89830	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877
89831	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371

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