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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL420501
Molecular formula	C26H28N6O4S2
IUPAC name	4-tert-butyl-N-[6-[2-(5-methylsulfanylpyrimidin-2-yl)oxyethoxy]-5-pyridin-4-ylpyrimidin-4-yl]benzenesulfonamide
Molecular weight	552.668
Hydrogen bond acceptor	11
Hydrogen bond donor	1
XlogP	4.4
Synonyms	4-tert-Butyl-N-{6-[2-(5-methylsulfanyl-pyrimidin-2-yloxy)-ethoxy]-5-pyridin-4-yl-pyrimidin-4-yl}-benzenesulfonamide BDBM50105016 SCHEMBL7481169
Inchi Key	GACZLMXVTORVRP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H28N6O4S2/c1-26(2,3)19-5-7-21(8-6-19)38(33,34)32-23-22(18-9-11-27-12-10-18)24(31-17-30-23)35-13-14-36-25-28-15-20(37-4)16-29-25/h5-12,15-17H,13-14H2,1-4H3,(H,30,31,32)
PubChem CID	11734340
ChEMBL	CHEMBL420501
IUPHAR	N/A
BindingDB	50105016
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
91515	Endothelin-1 receptor	Q29010	EDNRA	Sus scrofa (Pig)	427

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