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Ligand

Nameclomipramine
Molecular formulaC19H23ClN2
IUPAC name3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine
Molecular weight314.857
Hydrogen bond acceptor2
Hydrogen bond donor0
XlogP5.2
SynonymsChlorimipramine
303-49-1
Monochlorimipramine
3-Chloroimipramine
Hydiphen
[ Show all ]
Inchi KeyGDLIGKIOYRNHDA-UHFFFAOYSA-N
Inchi IDInChI=1S/C19H23ClN2/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3
PubChem CID2801
ChEMBLCHEMBL415
IUPHARN/A
BindingDB77970
DrugBankDB01242

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has a partition coefficient log P greater than 5.

Known GPCRs

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Total entries: 34
Page:  / 2 

GLASS IDNameUniProtGeneSpeciesLength
937345-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
937415-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
937105-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
937095-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
5558135-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
937255-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
937125-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
937155-hydroxytryptamine receptor 2CP08909Htr2cRattus norvegicus (Rat)460
937305-hydroxytryptamine receptor 6P31388Htr6Rattus norvegicus (Rat)436
937315-hydroxytryptamine receptor 6P50406HTR6Homo sapiens (Human)440
5558145-hydroxytryptamine receptor 7P32305Htr7Rattus norvegicus (Rat)448
93732Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
93739Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
93735Alpha-1B adrenergic receptorP15823Adra1bRattus norvegicus (Rat)515
93728Alpha-1D adrenergic receptorP25100ADRA1DHomo sapiens (Human)572
93711Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
93733Alpha-2B adrenergic receptorP18089ADRA2BHomo sapiens (Human)450
93736Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462
93740Alpha-2C adrenergic receptorP22086Adra2cRattus norvegicus (Rat)458
93719D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446

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